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GLP-1 medications used to treat diabetes and obesity may also help alleviate symptoms of anxiety and depression

The hormone GLP-1 is also a neurotransmitter and communicates directly with an area in the brain that regulates appetite, called the hypothalamus

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FGF21 is a newly discovered metabolic hormone produced in multiple tissues and secreted in the fasting state and regulates metabolic responses in the pancreas, liver and adipose tissues (95)